It is for that reason that desensitization to some substance to which an individual may be sensitive must be carried out very carefully and in such small doses that a severe reaction is not provoked.

正是由于这种原因，对某种可能引起个体敏感的物质，在进行脱敏时，必须谨慎从事，应当采用小剂量，以免激发严重反应。

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And it added in one case, a woman using black cohosh needed a liver transplantation after a particularly severe reaction.

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After one severe reaction, he said, most people consistently avoid the offending food and do not experience another severe attack.

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Alpha-gal's reactions vary on a case-by-case basis, sometimes with a patient experiencing a severe reaction and other times nothing at all.

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